Which are the key physics and statistical ingredients that we need to handle if we want to control swimmers transport under micro-confinement conditions? In this seminar i will summarize our numerical and experimental interdisciplinary contributions to the field of self propelled cells into microfluidics devices and its applications: E. Coli [1,2] and soil bacteria [3], human spermatozoa [4,5] and choanoflagellates [6].
I would like to show you how crucial is first to success in getting a good physical model of the micro-swimmers dynamics and statistics in order to be able to contribute to the design and optimization of real applications. We aimed to fabricate micro-devices for studying, directing, guiding, trapping, controlling and sorting cells in biomedicine, ecology, agronomy and evolutionary biology. These aims are being possible to be achieved thanks to a reach experimental-numerical feedback among molecular biologists, bio-technologists, bio-engineers and physicists.
By the end of this talk i hope to convince you how important is the contribution of physicists to this active field, showing the biology vs physics difficulties of the problems and the present challenges.
[1] I. Berdakin et al., PRE (2013)
[2] I. Berdakin et al. CEJP (2013)
[3] J. E. Quelas et al. Sci. Rep (2016)
[4] H. A. Guidobaldi et al. PRE (2014)
[5] H. A. Guidobaldi et al. Biomicrofluidics (2015)
[6] J. Sparacino et al. and G. Mino et al., preprints 2016